APLA Health, formerly the AIDS Project Los Angeles, is dedicated to improving the lives of people affected by HIV disease; reducing the incidence of HIV infection; and advocating for fair and effective HIV-related public policy.

In 2001, Meryl Streep designed the artwork for an AIDS Project Los Angeles’ holiday card campaign, alongside Hilary Swank, Lucy Liu, Valerie Rae Miller, Betsey Johnson, Peri Gilpin, Sean Hayes and Imitation of Christ. Created through a partnership with Soolip Paperie & Press, the holiday card program raised funds for services provided to men, women and children living with HIV and AIDS. Creativity kits created by APLA and Soolip Paperie & Press inspired the celebrities who let their imaginations run wild. Proceeds from the holiday card campaign will help support services that AIDS Project Los Angeles provides each year to more than 10,000 men, women and children living with HIV and AIDS including a food bank, child care, housing assistance, and professional dental care. The agency also provides prevention and treatment education, and advocates on local, state and federal levels on AIDS-related legislation.